Sr. Staff Scientist, Assay R&D at Personalis, Inc.

<p><span style="font-family: helvetica, arial, sans-serif; font-size: 12pt;">Based in Fremont, California, Personalis is a genome-oriented diagnostics company pioneering new paradigms in cancer management. We transform patient care through genomic characterization of tumors and ultrasensitive detection of disease recurrence or progression.&nbsp; To achieve this, we leverage whole-genome, exome, and bespoke targeted sequencing with proprietary algorithms to provide unmatched genetic accuracy.</span></p> <p><span style="font-family: helvetica, arial, sans-serif; font-size: 12pt;">Join a world-class, multidisciplinary team to drive impactful R&amp;D projects to improve our cutting-edge clinical offerings. Your work will advance a new generation of precision medicine products used by global biopharma and clinicians to transform cancer diagnostics and therapeutics.</span></p> <p><span style="font-family: helvetica, arial, sans-serif; font-size: 12pt;"><strong>Responsibilities:</strong></span></p> <ul> <li style="font-family: helvetica, arial, sans-serif; font-size: 12pt;"><span style="font-family: helvetica, arial, sans-serif; font-size: 12pt;">Organize and help perform internal proof of principle projects, development projects, and verification and validation exercises for liquid biopsy products in the Personalis portfolio.</span></li> <li style="font-family: helvetica, arial, sans-serif; font-size: 12pt;"><span style="font-family: helvetica, arial, sans-serif; font-size: 12pt;">Work with the broader R&amp;D organization to scope, track and troubleshoot liquid biopsy projects with internal and external collaborators and customers.</span></li> <li style="font-family: helvetica, arial, sans-serif; font-size: 12pt;"><span style="font-family: helvetica, arial, sans-serif; font-size: 12pt;">Collaborate with process development, tech transfer, and operations teams to shepherd early stage products, product revisions, and early projects through to operations.</span></li> <li style="font-family: helvetica, arial, sans-serif; font-size: 12pt;"><span style="font-family: helvetica, arial, sans-serif; font-size: 12pt;">Work with bioinformatics teams to plan experiments and analyze results.</span></li> <li style="font-family: helvetica, arial, sans-serif; font-size: 12pt;"><span style="font-family: helvetica, arial, sans-serif; font-size: 12pt;">Identify problems in current processes and come up with troubleshooting approaches and</span></li> <li style="font-family: helvetica, arial, sans-serif; font-size: 12pt;"><span style="font-family: helvetica, arial, sans-serif; font-size: 12pt;">Participate in meetings and present results.</span></li> <li style="font-family: helvetica, arial, sans-serif; font-size: 12pt;"><span style="font-family: helvetica, arial, sans-serif; font-size: 12pt;">Use effective two-way communication to create and maintain a collaborative working environment.</span></li> <li style="font-family: helvetica, arial, sans-serif; font-size: 12pt;"><span style="font-family: helvetica, arial, sans-serif; font-size: 12pt;">Support and ensure compliance with all department and company policies and procedures.</span></li> </ul> <p><span style="font-family: helvetica, arial, sans-serif; font-size: 12pt;"><strong>Education and Experience:</strong></span></p> <ul> <li style="font-family: helvetica, arial, sans-serif; font-size: 12pt;"><span style="font-family: helvetica, arial, sans-serif; font-size: 12pt;">Ph.D or MS with a minimum of 8 or 12 years of experience.</span></li> <li style="font-family: helvetica, arial, sans-serif; font-size: 12pt;"><span style="font-family: helvetica, arial, sans-serif; font-size: 12pt;">Minimum of 2 years of laboratory experience in NGS and/or liquid biopsy focused molecular biology.</span></li> <li style="font-family: helvetica, arial, sans-serif; font-size: 12pt;"><span style="font-family: helvetica, arial, sans-serif; font-size: 12pt;">Solid understanding of DNA/RNA manipulation.</span></li> <li style="font-family: helvetica, arial, sans-serif; font-size: 12pt;"><span style="font-family: helvetica, arial, sans-serif; font-size: 12pt;">Excellent organization, documentation and communication skills.</span></li> <li style="font-family: helvetica, arial, sans-serif; font-size: 12pt;"><span style="font-family: helvetica, arial, sans-serif; font-size: 12pt;">Passion for exploring new assays, hands-on experiment execution and creative thinking to solve problems.</span></li> <li style="font-family: helvetica, arial, sans-serif; font-size: 12pt;"><span style="font-family: helvetica, arial, sans-serif; font-size: 12pt;">Excellent ability to multitask and troubleshoot complex protocols.</span></li> <li style="font-family: helvetica, arial, sans-serif; font-size: 12pt;"><span style="font-family: helvetica, arial, sans-serif; font-size: 12pt;">Experience with automation (Hamilton or other liquid handlers) helpful.</span></li> <li style="font-family: helvetica, arial, sans-serif; font-size: 12pt;"><span style="font-family: helvetica, arial, sans-serif; font-size: 12pt;">ISO13485 validation experience helpful.</span></li> <li style="font-family: helvetica, arial, sans-serif; font-size: 12pt;"><span style="font-family: helvetica, arial, sans-serif; font-size: 12pt;">Data analysis skills with experience in Excel, JMP, R or Python.</span></li> <li style="font-family: helvetica, arial, sans-serif; font-size: 12pt;"><span style="font-family: helvetica, arial, sans-serif; font-size: 12pt;">Prior experience working with a LIMS directed environment.</span></li> <li style="font-family: helvetica, arial, sans-serif; font-size: 12pt;"><span style="font-family: helvetica, arial, sans-serif; font-size: 12pt;">Prior experience in cancer biology is strongly desired.</span></li> </ul> <p><span style="font-family: helvetica, arial, sans-serif; font-size: 12pt;">The hiring range for this position is<strong> </strong>$170,000 to $200,000 per year, which may factor in various geographic regions. The base pay actually offered will take into account internal equity and also may vary depending on the candidate’s geographic region, job-related knowledge, skills, and experience among other factors. Our full-time regular positions also include an annual performance-based bonus (or a sales incentive plan) and long-term incentive units (equity) provided as part of our compensation package, in addition to a full range of medical, financial, and/or other benefits, dependent on the level and position offered.</span></p> <p style="text-align: left;"><span style="font-family: helvetica, arial, sans-serif; font-size: 12pt;">Personalis is an equal opportunity employer and is committed to the full inclusion of all individuals. As part of this commitment, Personalis will ensure that persons with disabilities are provided with reasonable accommodations. If you need an accommodation to participate in the job application or interview process, to perform essential job functions, and/or to receive other benefits and privileges of employment, please let your recruiter know, if/when they contacts you.</span></p> <p style="text-align: left;"><span style="font-family: helvetica, arial, sans-serif; font-size: 12pt;"><strong>Protecting Our Candidates:</strong> At Personalis, we value your security. Please note that all official correspondence from our team will come exclusively from <strong>@</strong><a href="http://personalis.com" target="_blank"><strong>personalis.com</strong></a> email addresses. We will never ask for personal financial information or conduct interviews over text or chat platforms. If you receive a suspicious request, it is likely a scam. We are committed to a safe recruitment experience and actively work with authorities to investigate and prosecute cyber crimes targeting our community.</span></p> <p><span style="font-family: helvetica, arial, sans-serif; font-size: 12pt;"><em>Personalis is an Equal Opportunity Employer/Minorities/Females/Veterans/Disabilities. Personalis offers a competitive compensation package and benefits including medical,&nbsp;dental, vision, 401(k) match, ESPP, tuition reimbursement, sick/vacation time, commuter benefits/ EV charging stations, onsite gym, and wellness benefits. (For US only, benefits in other countries may vary.)&nbsp;</em></span></p> <p>&nbsp;</p> <p><span style="font-family: helvetica, arial, sans-serif; font-size: 12pt;"><em><span data-sheets-root="1">#LI-KK1 #LI-Onsite</span></em></span></p> <p>&nbsp;</p>