Clinical Prompt Engineer at Truveta

<p>&nbsp;</p> <p><span data-contrast="auto">Truveta provides unprecedented real-world data and real-time intelligence, powered by a dataset built with and owned by US health systems united in a mission of Saving Lives with Data. Together, we power breakthrough&nbsp;medical&nbsp;discoveries, accelerate regulatory-grade evidence, and improve patient care.&nbsp;Today, Truveta&nbsp;enables research on more than 130 million&nbsp;de-identified&nbsp;patients across the US.&nbsp;</span><span data-ccp-props="{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;201341983&quot;:0,&quot;335551550&quot;:1,&quot;335551620&quot;:1,&quot;335559685&quot;:0,&quot;335559737&quot;:0,&quot;335559738&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:278}">&nbsp;</span></p> <p><span data-contrast="auto">Achieving Truveta’s ambitious&nbsp;mission&nbsp;requires&nbsp;an incredible team of talented and inspired people with a special combination of health, software and big data experience who share&nbsp;our </span><a href="https://www.truveta.com/careers/"><span data-contrast="auto">company values</span></a><span data-contrast="auto">.</span><span data-ccp-props="{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;201341983&quot;:0,&quot;335551550&quot;:1,&quot;335551620&quot;:1,&quot;335559685&quot;:0,&quot;335559737&quot;:0,&quot;335559738&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:278}">&nbsp;</span></p> <p><span data-ccp-props="{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;201341983&quot;:0,&quot;335551550&quot;:1,&quot;335551620&quot;:1,&quot;335559685&quot;:0,&quot;335559737&quot;:0,&quot;335559738&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:278}">Role Overview</span></p> <p>We are hiring a Prompt Engineer with a strong clinical informatics background to build and optimize AI prompts for healthcare and clinical data applications. This role requires hands-on clinical understanding, experience working with real clinical data, experience writing prompts for AI models, and the ability to align LLM prompts with underlying clinical data models.</p> <p>You will work closely with clinicians, data engineers, and AI teams to translate clinical questions and workflows into accurate, safe, and scalable AI interactions.</p> <p>Key Responsibilities</p> <ul> <li>Design, test, and optimize prompts for LLM-based clinical use cases such as:</li> <ul> <li>Cohort identification</li> <li>Clinical question answering</li> <li>Concept extraction</li> <li>Clinical code mapping</li> </ul> <li>Translate clinical requirements into structured prompts aligned with clinical data schemas</li> <li>Collaborate with data engineers to understand how diagnoses, labs, medications, encounters, and outcomes are modeled</li> <li>Evaluate AI outputs for clinical accuracy, relevance, bias, and safety</li> <li>Apply healthcare data standards (FHIR, SNOMED CT, LOINC, RxNorm, ICD-10-CM) within prompt logic and validation</li> <li>Create prompt evaluation criteria and quality benchmarks</li> <li>Document reusable prompt patterns and best practices</li> <li>Continuously improve prompts based on model behavior and user feedback.</li> </ul> <p>Required Qualifications</p> <ul> <li>2–5 years of experience in clinical informatics, healthcare analytics, or health IT</li> <li>Clinical background required, such as:</li> <ul> <li>Nursing, pharmacy, medicine, public health, or clinical informatics</li> <li>OR hands-on experience working with clinical workflows or EHR data</li> </ul> <li>Strong understanding of clinical data modeling, including representation of:</li> <ul> <li>Diagnoses, procedures, medications</li> <li>Laboratory results and vitals</li> <li>Encounters and outcomes</li> </ul> <li>Practical experience with healthcare data standards:</li> <ul> <li>FHIR</li> <li>SNOMED CT</li> <li>LOINC</li> <li>RxNorm</li> <li>ICD-10-CM</li> </ul> <li>Hands-on experience with LLMs and prompt engineering for applied or production use cases</li> <li>Ability to critically evaluate AI outputs for correctness and clinical safety</li> <li>Strong analytical, documentation, and communication skills</li> </ul> <p>Preferred</p> <ul> <li>Experience with clinical NLP or unstructured clinical text</li> <li>Familiarity with EHR systems or clinical data repositories</li> <li>Working knowledge of Python for prompt testing or evaluation</li> <li>Working knowledge of SQL for exploring clinical datasets</li> <li>Experience combining structured and unstructured healthcare data</li> <li>Prior work on healthcare AI, decision support, or analytics platforms</li> </ul>