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Alamar Biosciences, Inc. logo

Alamar Biosciences, Inc.

Sr. Mechanical Engineer at Alamar Biosciences, Inc.

Fremont, CaliforniaFull-timeInstrument DevelopmentPosted about 1 month ago
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About the Role

<div class="content-intro"><p><span style="font-family: helvetica, arial, sans-serif; font-size: 12pt;">At Alamar, we are passionate about enabling our customers to make scientific discoveries that translate into clinical outcomes and benefit patients. Our team is growing quickly as we develop innovative approaches to measure critical protein biomarkers from liquid samples that can enable the earliest possible detection of disease. We believe the next frontier in biology is enabled by measuring proteins at higher sensitivity in highly multiplexed assays at the push of a button, which is something only Alamar can do. As we build our team, we seek collaborative, driven, intellectually curious people committed to solving complex challenges. Our culture rewards accountability and cross functional teamwork because we believe this enables the kind of breakthrough thinking that will accelerate our mission.</span></p></div><p><span style="font-size: 12pt;">As a Senior Mechanical Engineer, you will play a critical role in sustaining our current proteomics instrument platform while driving the development of next-generation systems. You will collaborate with cross-functional teams—including R&amp;D scientists, system engineers, software developers, and manufacturing experts—to ensure reliability, optimize performance, and innovate robust solutions. This role demands hands-on expertise, creative problem-solving, and a passion for advancing biotech instrumentation in a fast-paced startup environment.</span></p> <p><span style="font-size: 12pt;"><strong>Key Responsibilities</strong></span></p> <ul> <li style="font-size: 12pt;"><span style="font-size: 12pt;">Sustaining Engineering: Own mechanical reliability improvement projects (life testing, FMEA updates, failure analysis).</span></li> <li style="font-size: 12pt;"><span style="font-size: 12pt;">Drive design changes via ECOs and partner with Manufacturing to validate fixes.</span></li> <li style="font-size: 12pt;"><span style="font-size: 12pt;">Next-Generation Development: Build and bring‑up alpha/beta prototypes; define verification methods (gage R&amp;R, test fixtures, acceptance criteria) and analyze results to iterate designs.</span></li> <li style="font-size: 12pt;"><span style="font-size: 12pt;">Partner with Systems/Software/Vendor to integrate sensors/actuators; define interfaces, alignment/adjustment schemes, and calibration methods.</span></li> <li style="font-size: 12pt;"><span style="font-size: 12pt;">CAD: Develop and maintain 3D CAD models and assemblies using SolidWorks. Release production drawings with full GD&amp;T and critical‑to‑quality callouts.</span></li> <li style="font-size: 12pt;"><span style="font-size: 12pt;">Hands-On Execution: Perform assembly, testing, and debugging in lab settings using diagnostic tools and equipment to verify functionality. Develop and validate testing or manufacturing fixtures.</span></li> <li style="font-size: 12pt;"><span style="font-size: 12pt;">Documentation: own BOMs, CAD, and production drawings with full GD&amp;T; ensure change of traceability, serviceability, backwards compatibility and smooth change management with CM.</span></li> <li style="font-size: 12pt;"><span style="font-size: 12pt;">Manufacturing Integration: Identify advanced materials, suppliers and processes (e.g., injection molding, CNC machining, sheet metal fabrication) to improve cost-efficiency and system robustness.</span></li> </ul> <p><span style="font-size: 12pt;"><strong>Requirements:</strong></span></p> <ul> <li style="font-size: 12pt;"><span style="font-size: 12pt;">Education: Bachelor’s or Master’s degree in Mechanical Engineering, Mechatronics, or a related field.</span></li> <li style="font-size: 12pt;"><span style="font-size: 12pt;">Experience: 6+ years in mechanical engineering for biotech instrumentation, medical devices, or life sciences platforms (e.g., NGS sequencers, PCR analyzers, or protein detection systems), with expertise in both sustaining and developing complex electro-mechanical systems.</span></li> </ul> <p><span style="font-size: 12pt;">Technical Skills:</span></p> <ul> <li style="font-size: 12pt;"><span style="font-size: 12pt;">Expert in 3D CAD modeling (SolidWorks preferred)</span></li> <li style="font-size: 12pt;"><span style="font-size: 12pt;">Experience designing precision gantry systems (e.g., XY/XYZ): linear guides, belts/lead screws/ball screws, stepper/BLDC drives, kinematics and backlash management, alignment/calibration methods, tolerance analysis, and safety/interlocks.</span></li> <li style="font-size: 12pt;"><span style="font-size: 12pt;">Expertise in mechanisms, materials, GD&amp;T, and tolerance analysis.</span></li> <li style="font-size: 12pt;"><span style="font-size: 12pt;">Proficiency in structured problem-solving, verification/validation (V&amp;V), and risk management processes.</span></li> </ul> <p><span style="font-size: 12pt;">Soft Skills:</span></p> <ul> <li style="font-size: 12pt;"><span style="font-size: 12pt;">Excellent analytical, problem-solving, written, and verbal communication skills.</span></li> <li style="font-size: 12pt;"><span style="font-size: 12pt;">Ability to collaborate across disciplines and present technical concepts clearly to non-experts.</span></li> <li style="font-size: 12pt;"><span style="font-size: 12pt;">Proactive, adaptable, and thrive in a fast-paced startup environment with a strong sense of ownership.</span></li> </ul> <p><span style="font-size: 12pt;">Preferred Qualifications:</span></p> <ul> <li style="font-size: 12pt;"><span style="font-size: 12pt;">Demonstrated ownership from concept → V&amp;V → transfer to manufacturing → sustaining for a complex instrument or subsystem.</span></li> <li style="font-size: 12pt;"><span style="font-size: 12pt;">Background in machined, sheet metal, and injection molded parts and their production tooling.</span></li> <li style="font-size: 12pt;"><span style="font-size: 12pt;">Experience with biotech-specific challenges, such as integrating consumables, liquid-handling, or thermal control in high-throughput instruments.</span></li> <li style="font-size: 12pt;"><span style="font-size: 12pt;">Knowledge of ISO 13485 and other regulatory standards for medical devices or diagnostics.</span></li> </ul> <p><span style="font-size: 12pt;">The base salary range for this full-time position is $150,000 - $170,000 + bonus + equity + benefits. Our salary ranges are determined by work location, job-related skills, experience, and relevant education or training. The ranges displayed on each job posting reflect the minimum and maximum target for new hire salaries but are subject to change if the leveling of the role is adjusted. Your recruiter can share more about the specific salary range during the hiring process.&nbsp;</span></p>

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