Process Engineering Co-op, LNP Development at Beam Therapeutics

Cambridge, MAInternshipLNP PlatformsPosted about 1 month ago

About the Role

<div class="content-intro"> Company Overview: Beam Therapeutics is a biotechnology company committed to establishing the leading, fully integrated platform for precision genetic medicines. To achieve this vision, Beam has assembled a platform with integrated gene editing, delivery and internal manufacturing capabilities. Beam’s suite of gene editing technologies is anchored by base editing, a proprietary technology that is designed to enable precise, predictable and efficient single base changes, at targeted genomic sequences, without making double-stranded breaks in the DNA. This has the potential to enable a wide range of therapeutic editing strategies that Beam is using to advance a diversified portfolio of base editing programs. Beam is a values-driven organization committed to its people, cutting-edge science, and a vision of providing life-long cures to patients suffering from serious diseases. </div>Position Overview:  Beam is looking for a highly energetic Process Engineering Co-op to join our growing LNP Development Team from January through June 2027.  In this role, you will contribute to scale-up activities for Lipid Nanoparticle formulations and process development, troubleshooting strategies and data driven experimental designs for next-generation LNP formulations. You will work closely with the development team along with collaborating cross-functionally within a fast-paced environment to develop robust and scalable LNPs.  Responsibilities:  <ul> <li data-leveltext="" data-font="Symbol" data-listid="6" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="1" data-aria-level="1">Support the development, optimization, and scale-up of targeted lipid nanoparticle (tLNP) manufacturing processes. </li> <li data-leveltext="" data-font="Symbol" data-listid="6" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="1" data-aria-level="1">Conduct formulation and process development studies involving LNP mixing, filtration, and tangential flow filtration (TFF) to evaluate and understand key product quality attributes.  </li> <li data-leveltext="" data-font="Symbol" data-listid="6" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="1" data-aria-level="1">Execute laboratory experiments to assess process performance and characterize the impact of critical process parameters on LNP quality, stability, and manufacturability.  </li> <li data-leveltext="" data-font="Symbol" data-listid="6" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="1" data-aria-level="1">Contribute to process improvement initiatives through experimental design, data analysis, and troubleshooting of formulation and manufacturing challenges.  </li> <li data-leveltext="" data-font="Symbol" data-listid="6" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="1" data-aria-level="1">Collaborate with cross-functional teams across LNP Development, Analytical Development, and Process Optimization to advance project objectives. </li> <li data-leveltext="" data-font="Symbol" data-listid="6" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="1" data-aria-level="1">Maintain accurate documentation of experimental activities, analyze results, and present to the project team.</li> <li data-leveltext="" data-font="Symbol" data-listid="6" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="1" data-aria-level="1">Follow all laboratory safety policies and procedures while supporting routine laboratory operations. </li> </ul> Qualifications:  <ul> <li data-leveltext="" data-font="Symbol" data-listid="7" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="1" data-aria-level="1">Pursuing a BS or MS in Bioengineering, Biochemistry or any related field of study with at least 1 year of relevant experience.</li> <li data-leveltext="" data-font="Symbol" data-listid="7" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="1" data-aria-level="1">Strong interest in drug delivery, bioprocess development, or pharmaceutical manufacturing.  </li> <li data-leveltext="" data-font="Symbol" data-listid="7" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="1" data-aria-level="1">Knowledge of Excel, PowerPoint, and data analytics tools required</li> <li data-leveltext="" data-font="Symbol" data-listid="7" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="1" data-aria-level="1">Comfortable working in a highly collaborative, fast-paced environment with cross-functional teams.  </li> <li data-leveltext="" data-font="Symbol" data-listid="7" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="1" data-aria-level="1">Strong analytical and critical thinking skills, with familiarity with process engineering concepts.  </li> <li data-leveltext="" data-font="Symbol" data-listid="7" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="1" data-aria-level="1">Highly motivated to learn, with excellent organizational, communication, and time management skills.</li> <li data-leveltext="" data-font="Symbol" data-listid="7" data-list-defn-props="{"335552541":1,"335559685":720,"335559991":360,"469769226":"Symbol","469769242":[8226],"469777803":"left","469777804":"","469777815":"multilevel"}" data-aria-posinset="1" data-aria-level="1">Applicants must be currently enrolled in a degree-granting college or university program and maintain their student status throughout the duration of the co-op to be eligible. </li> </ul><div class="content-pay-transparency"><div class="pay-input"><div class="description">Hourly pay will will be determined based on several factors, including but not limited to, relevant experience, skills, and education.</div><div class="title">Co-op Hourly Pay Range</div><div class="pay-range">$23—$34 USD</div></div></div>

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