Bioinformatics/Data Scientist at Axle

<div style="font-size: 10pt; font-family: 'Tahoma';"> <p>(ID: 2025-0696)</p> <br> <p><strong>Axle</strong> is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).</p> <p>&nbsp;</p> <p><strong>Axle</strong> is seeking a <strong><em>Bioinformatics/Data Scientist</em></strong> to join our vibrant team at the National Institutes of Health (NIH) supporting the Standardized Organoid Model Center in <strong>Frederick, MD. </strong><span style="color: black; font-family: Tahoma; font-size: 10pt;">The Standardized Organoid Model Center is an NIH-funded initiative dedicated to advancing organoid research through the development of validated, reproducible, and well-characterized organoid models. The center brings together interdisciplinary teams of researchers to establish standardized protocols, develop quality control measures, and create resources that will benefit the broader organoid research community.</span></p> </div> <p>&nbsp;</p> <div style="font-size: 10pt; font-family: 'Tahoma';"> <p><strong>Benefits We Offer:</strong></p> <ul> <li>100% Medical, Dental &amp; Vision Coverage for Employees</li> <li>Paid Time Off and Paid Holidays</li> <li>401K match up to 5%</li> <li>Educational Benefits for Career Growth</li> <li>Employee Referral Bonus</li> <li>Flexible Spending Accounts: <ul> <li>Healthcare (FSA)</li> <li>Parking Reimbursement Account (PRK)</li> <li>Dependent Care Assistant Program (DCAP)</li> <li>Transportation Reimbursement Account (TRN)</li> </ul> </li> </ul> </div> <div class="ck-content" style="font-family: Segoe UI; font-size: 11pt;" data-wrapper="true"> <div class="ck-content stickystyles-wrapper-insert" style="font-family: Segoe UI; font-size: 11pt;" data-wrapper="true"> <p style="line-height: normal; margin: 0in 0in 8pt;">&nbsp;</p> <p style="line-height: normal; margin: 0in 0in 8pt;"><span style="color: black; font-family: Tahoma; font-size: 10pt;"><strong>Overview</strong></span></p> <p style="line-height: normal; margin: 0in 0in 8pt;"><span style="color: black; font-family: Tahoma; font-size: 10pt;">The Bioinformatics/Data Scientist will conduct comprehensive analyses of multi-omics data generated from organoid systems and corresponding normal tissues. This position is central to the SOM Center's research objectives, focusing on characterizing organoid fidelity, identifying biomarkers of successful differentiation, and developing computational frameworks for organoid quality assessment.</span></p> <p style="line-height: normal; margin: 0in 0in 8pt;">&nbsp;</p> <p style="line-height: normal; margin: 0in 0in 8pt;"><span style="color: black; font-family: Tahoma; font-size: 10pt;"><strong>Responsibilities</strong></span></p> <ul> <li style="line-height: normal;"><span style="color: black; font-family: Tahoma; font-size: 10pt;">The successful candidate will analyze complex datasets including single-cell RNA sequencing, bulk RNA sequencing, proteomics, and metabolomics data from various organoid systems and their tissue counterparts.</span></li> <li style="line-height: normal;"><span style="color: black; font-family: Tahoma; font-size: 10pt;">The position will develop and implement computational pipelines for data processing, quality control, and statistical analysis.</span></li> <li style="line-height: normal;"><span style="color: black; font-family: Tahoma; font-size: 10pt;">A major component of the role involves integrating SOM-generated data with publicly available datasets to benchmark organoid characteristics against normal tissue profiles.</span></li> <li style="line-height: normal;"><span style="color: black; font-family: Tahoma; font-size: 10pt;">The position requires close collaboration with experimental teams to interpret results and guide protocol optimization, as well as contributing to manuscript preparation and presenting findings at scientific conferences.</span></li> </ul> <p style="line-height: normal; margin: 0in 0in 8pt;">&nbsp;</p> <p style="line-height: normal; margin: 0in 0in 8pt;"><span style="color: black; font-family: Tahoma; font-size: 10pt;"><strong>Required Qualifications</strong></span></p> <ul> <li style="line-height: normal;"><span style="color: black; font-family: Tahoma; font-size: 10pt;">Candidates must hold a PhD in bioinformatics, computational biology, biostatistics, or a related quantitative field.</span></li> <li style="line-height: normal;"><span style="color: black; font-family: Tahoma; font-size: 10pt;">Extensive experience with single-cell data analysis, including familiarity with tools such as Seurat, Scanpy, or similar platforms, is essential.</span></li> <li style="line-height: normal;"><span style="color: black; font-family: Tahoma; font-size: 10pt;">Strong programming skills in R and Python are required, along with experience in statistical analysis and data visualization.</span></li> <li style="line-height: normal;"><span style="color: black; font-family: Tahoma; font-size: 10pt;">Knowledge of proteomics and metabolomics data analysis workflows is necessary.</span></li> </ul> <p style="line-height: normal; margin: 0in 0in 8pt;">&nbsp;</p> <p style="line-height: normal; margin: 0in 0in 8pt;"><span style="color: black; font-family: Tahoma; font-size: 10pt;"><strong>Preferred Qualifications</strong></span></p> <ul> <li style="line-height: normal;"><span style="color: black; font-family: Tahoma; font-size: 10pt;">Previous experience analyzing organoid datasets is strongly preferred.</span></li> <li style="line-height: normal;"><span style="color: black; font-family: Tahoma; font-size: 10pt;">Experience with machine learning approaches for biological data, familiarity with pathway analysis tools, and knowledge of developmental biology principles will be considered valuable assets.</span></li> <li style="line-height: normal;"><span style="color: black; font-family: Tahoma; font-size: 10pt;">Experience with high-performance computing environments and version control systems is desirable.</span></li> </ul> </div> </div> <p>&nbsp;</p> <div style="font-size: 10pt; font-family: 'Tahoma'; text-align: center;"> <p><strong>Disclaimer:</strong> The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.</p> <p>The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.</p> <p>Accessibility: If you need an accommodation as part of the employment process please contact: <span style="color: black;"><a href="mailto:[email protected]" target=" _blank">[email protected]</a> </span></p> <p>This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.</p> <p>#INDPSD</p> </div><div class="content-pay-transparency"><div class="pay-input"><div class="title">Salary Range</div><div class="pay-range"><span>$105,000</span><span class="divider">&mdash;</span><span>$120,000 USD</span></div></div></div>